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Keap1 mutation renders lung adenocarcinomas dependent on Slc33a1.
Romero R, Sánchez-Rivera FJ, Westcott PMK, Mercer KL, Bhutkar A, Muir A, González Robles TJ, Lamboy Rodríguez S, Liao LZ, Ng SR, Li L, Colón CI, Naranjo S, Beytagh MC, Lewis CA, Hsu PP, Bronson RT, Vander Heiden MG, Jacks T. Romero R, et al. Among authors: beytagh mc. Nat Cancer. 2020 Jun;1(6):589-602. doi: 10.1038/s43018-020-0071-1. Epub 2020 Jun 8. Nat Cancer. 2020. PMID: 34414377 Free PMC article.
A Molecular Switch between Mammalian MLL Complexes Dictates Response to Menin-MLL Inhibition.
Soto-Feliciano YM, Sánchez-Rivera FJ, Perner F, Barrows DW, Kastenhuber ER, Ho YJ, Carroll T, Xiong Y, Anand D, Soshnev AA, Gates L, Beytagh MC, Cheon D, Gu S, Liu XS, Krivtsov AV, Meneses M, de Stanchina E, Stone RM, Armstrong SA, Lowe SW, Allis CD. Soto-Feliciano YM, et al. Among authors: beytagh mc. Cancer Discov. 2023 Jan 9;13(1):146-169. doi: 10.1158/2159-8290.CD-22-0416. Cancer Discov. 2023. PMID: 36264143 Free PMC article.
EGFR ligands dictate tumour suppression.
Beytagh MC, Weiss WA. Beytagh MC, et al. Nat Cell Biol. 2022 Aug;24(8):1189-1191. doi: 10.1038/s41556-022-00967-z. Nat Cell Biol. 2022. PMID: 35915160 Free PMC article.
Identification of DHODH as a therapeutic target in small cell lung cancer.
Li L, Ng SR, Colón CI, Drapkin BJ, Hsu PP, Li Z, Nabel CS, Lewis CA, Romero R, Mercer KL, Bhutkar A, Phat S, Myers DT, Muzumdar MD, Westcott PMK, Beytagh MC, Farago AF, Vander Heiden MG, Dyson NJ, Jacks T. Li L, et al. Among authors: beytagh mc. Sci Transl Med. 2019 Nov 6;11(517):eaaw7852. doi: 10.1126/scitranslmed.aaw7852. Sci Transl Med. 2019. PMID: 31694929 Free PMC article.
Mitochondrial apoptotic priming is a key determinant of cell fate upon p53 restoration.
Sánchez-Rivera FJ, Ryan J, Soto-Feliciano YM, Clare Beytagh M, Xuan L, Feldser DM, Hemann MT, Zamudio J, Dimitrova N, Letai A, Jacks T. Sánchez-Rivera FJ, et al. Among authors: clare beytagh m. Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2019740118. doi: 10.1073/pnas.2019740118. Proc Natl Acad Sci U S A. 2021. PMID: 34074758 Free PMC article.
Publisher Correction: Keap1 mutation renders lung adenocarcinomas dependent on Slc33a1.
Romero R, Sánchez-Rivera FJ, Westcott PMK, Mercer KL, Bhutkar A, Muir A, González Robles TJ, Rodríguez SL, Liao LZ, Ng SR, Li L, Colón CI, Naranjo S, Beytagh MC, Lewis CA, Hsu PP, Bronson RT, Vander Heiden MG, Jacks T. Romero R, et al. Among authors: beytagh mc. Nat Cancer. 2020 Sep;1(9):935. doi: 10.1038/s43018-020-00118-z. Nat Cancer. 2020. PMID: 35121957 No abstract available.